A Framework for XML-based Integration of Data visualization and Analysis in a Biomedical Domain ===================================================================== Biomedical data are becoming increasingly complex and heterogeneous in nature. The data are stored in distributed information systems, using a variety of data models, and are processed by increasingly more complex tools that analyze and visualize them. We present in this talk our framework for integrating biomedical research data and tools into a unique Web front end. Our framework is applied to the University of Washington's Human Brain Project. Speci?cally, we present solutions to four integration tasks: de?nition of complex mappings from relational sources to XML, distributed XQuery processing, generation of heterogeneous output formats, and the integration of heterogeneous data visualization and analysis tools.